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Активные фармацевтические вещества

Активные фармацевтические вещества

Гриндекс – Ваш выбор №1 в сфере активных фармацевтических веществ (АФВ).

Наши АФВ производятся в соответствии с требованиями GMP, сертифицированы разрешением (лицензией) на производство АФВ и Сертификатом GMP надлежащей производственной практики.

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Status

Usage

A-Z

Oxytocin
INN
Oxytocin
Quality application
Ph. Eur. CEP (Cerificate of Suitability),Ph. Eur. ASMF, USP VMF Complete Document
Therapeutic use
Uterotonic
CAS number
50-56-6
Dexmedetomidine hydrochloride
INN
Dexmedetomidine hydrochloride
Quality application
Ph. Eur. ASMF, USP, JP / Ph. Eur.
Therapeutic use
Sedative
CAS number
145108-58-3
Xylazine hydrochloride
INN
Xylazine hydrochloride
Quality application
Ph. Eur. CEP (Cerificate of Suitability), Ph. Eur. ASMF, USP ASMF
Therapeutic use
Sedative, analgesic, muscle relaxant
CAS number
23076-35-9
Oxytocin
INN
Oxytocin
Quality application
Ph. Eur. CEP (Cerificate of Suitability),Ph. Eur. ASMF, USP VMF
Therapeutic use
Uterotonic
CAS number
50-56-6
Dexmedetomidine hydrochloride
INN
Dexmedetomidine hydrochloride
Quality application
Ph. Eur. ASMF
Therapeutic use
Sedative
CAS number
145108-58-3
Ropinirole
INN
Ropinirole
Quality application
Ph. Eur. ASMF
Therapeutic use
Anti-Parkinson drugs
CAS number
91374-21-9 91374-20-8 (HCl)
Dorzolamide
INN
Dorzolamide
Quality application
Ph. Eur. ASMF
Therapeutic use
Ophthalmic
CAS number
120279-96-1 (base) 130693-82-2 (Hcl)
Caspofungin
INN
Caspofungin
Quality application
Ph. Eur. ASMF
Therapeutic use
Antifungals
CAS number
179463-17-3
Anidulafungin
INN
Anidulafungin
Quality application
Ph. Eur. ASMF
Therapeutic use
Antifungals
CAS number
166663-25-8
Alfentanil
INN
Alfentanil
Quality application
Ph. Eur. ASMF
Therapeutic use
Opioid
CAS number
70879-28-6 71195-58-9 (base)
Edoxaban
INN
Edoxaban
Quality application
JP, Ph. Eur. ASMF
Therapeutic use
Anticoagulant
CAS number
480449-70-5
Alprazolam
INN
Alprazolam
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Sedative
CAS number
28981-97-7
Vortioxetine
INN
Vortioxetine
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Antidepressants
CAS number
508233-74-7
Linagliptin
INN
Linagliptin
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antidiabetic
CAS number
668270-12-0
Tofacitinib
INN
Tofacitinib
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Selective immunosuppressants
CAS number
477600-75-2
Apremilast
INN
Apremilast
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Selective immunosuppressants
CAS number
608141-41-9
Empagliflozin
INN
Empagliflozin
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antidiabetic
CAS number
864070-44-0
Lisdexamfetamine
INN
Lisdexamfetamine
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Psychostimulants
CAS number
608137-32-2
Oxaliplatin
INN
Oxaliplatin
Quality application
JP, Ph. Eur. ASMF
Therapeutic use
Antineoplastic
CAS number
61825-94-3
Voriconazole
INN
Voriconazole
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antifungals
CAS number
137234-62-9
Nepafenac
INN
Nepafenac
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
78281-72-8
Latanoprost
INN
Latanoprost
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
130209-82-4
Micafungin sodium
INN
Micafungin sodium
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antifungals
CAS number
208538-73-2
Timolol
INN
Timolol
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
26839-75-8
Irinotecan
INN
Irinotecan
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antineoplastic
CAS number
97682-44-5
Brinzolamide
INN
Brinzolamide
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
138890-62-7
Travoprost
INN
Travoprost
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
157283-68-6
Carfilzomib
INN
Carfilzomib
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antineoplastic
CAS number
868540-17-4
Bimatoprost
INN
Bimatoprost
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Ophthalmic
CAS number
155206-00-1
Pemetrexed disodium
INN
Pemetrexed disodium
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Antineoplastic
CAS number
150399-23-8 357166-30-4
Sugammadex
INN
Sugammadex
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Selective relaxant binding agent
CAS number
343306-71-8
Dapagliflozin
INN
Dapagliflozin
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Diabete
CAS number
461432-26-8
Apixaban
INN
Apixaban
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Anticoagulant
CAS number
503612-47-3
Nilotinib
INN
Nilotinib
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Cytostatic
CAS number
641571-10-0
Rocuronium bromide
INN
Rocuronium bromide
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Muscle relaxant
CAS number
119302-91-9
Esketamine
INN
Esketamine
Quality application
Ph. Eur. ASMF, USP
Therapeutic use
Anesthetic
CAS number
33643-46-8
Remifentanil
INN
Remifentanil
Quality application
JP, Ph. Eur. ASMF, USP
Therapeutic use
Opioid
CAS number
132539-07-2
Zopiclone
INN
Zopiclone
Quality application
Ph. Eur. CEP (Certificate of Suitability), Ph. Eur. ASMF, CA ASMF
Therapeutic use
Hypnotic
CAS number
43200-80-2
Droperidol
INN
Droperidol
Quality application
Ph. Eur. CEP, Ph. Eur. ASMF, USP ASMF, JP/ USP
Therapeutic use
Neuroleptic
CAS number
548-73-2
Xylazine
INN
Xylazine
Quality application
USP VMF Complete Document, USP ASMF
Therapeutic use
Sedative, analgesic, muscle relaxant (vet.)
CAS number
7361-61-7
Status
Commercially available
Usage
For veterinary use
Chemical name
N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
Structure
Xylazine
Sufentanil
INN
Sufentanil
Quality application
Ph. Eur. ASMF
Therapeutic use
Opioid
CAS number
60561-17-3
Usage
For human use
Chemical name
N-[4-(Methoxymethyl)-1-(2-thiofuran-2-ylethyl)-4-piperidyl]-N-phenylpropanamide citrate
Structure
api6
Rilmenidini dihydrogenphosphas
INN
Rilmenidini dihydrogenphosphas
Quality application
Ph. Eur. ASMF
Therapeutic use
Antihypertensive
CAS number
85409-38-7
Status
Commercially available
Usage
For human use
Chemical name
N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine dihydrogen phosphate
Structure
Rilmenidine
Norepinephrine / noradrenaline
INN
Norepinephrine / noradrenaline
Quality application
Ph. Eur. ASMF
Therapeutic use
Cardiac therapy
CAS number
51-41-2 108341-18-0 (tartrate H2O)
Usage
For human use
Chemical name
(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol l-tartrate
Structure
Norepinephrine_noradrenaline
Mivacurium chloride
INN
Mivacurium chloride
Quality application
Ph. Eur. ASMF
Therapeutic use
Muscle relaxant
CAS number
106861-44-3
Usage
For human use
Chemical name
(1R,1’R)-2,2′-[[(4E)-1,8-dioxooct-4-ene-1,8-diyl]bis(oxypropane-3,1-diyl)]bis[6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolinium] dichloride
Structure
9api
Medetomidini hydrochloride
INN
Medetomidini hydrochloride
Quality application
Ph. Eur. ASMF, USP VMF Complete Document
Therapeutic use
Sedative, analgesic (vet.)
CAS number
86347-15-1
Status
Commercially available
Usage
For veterinary use
Chemical name
4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
Structure
Medetomidine
Levosimendan
INN
Levosimendan
Quality application
Ph. Eur. ASMF
Therapeutic use
Cardiac therapy
CAS number
141505-33-1
Status
Commercially available
Usage
For human use
Chemical name
2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile
Structure
api
Imatinib mesylate
INN
Imatinib mesylate
Quality application
Ph. Eur. ASMF
Therapeutic use
Antineoplastic
CAS number
220127-57-1
Status
Commercially available
Usage
For human use
Chemical name
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide mesilate
Structure
api_3
Fentanyl
INN
Fentanyl
Quality application
Ph. Eur. ASMF, USP*
Therapeutic use
Opioid
CAS number
990-73-8
Status
Expected availability 2022 Q3
Usage
For human use
Chemical name
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide citrate
Structure
fentanyl
Fentanil base
INN
Fentanil base
Quality application
Ph. Eur. ASMF, JP*, USP*
Therapeutic use
Opioid
CAS number
437-38-7
Status
Expected availability 2022 Q3
Usage
For human use
Chemical name
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
Structure
fentanyl_bse
Detomidine hydrochloride
INN
Detomidine hydrochloride
Quality application
Ph. Eur. ASMF, USP VMF Complete Document
Therapeutic use
Sedative (vet.)
CAS number
90038-01-0
Status
Commercially available
Usage
For veterinary use
Chemical name
4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole hydrochloride
Structure
Detomidine
Cisatracurium bezilate
INN
Cisatracurium bezilate
Quality application
Ph. Eur. ASMF (available first), USP
Therapeutic use
Muscle relaxant
CAS number
96946-42-8
Usage
For human use
Chemical name
5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate dibenzenesulfonate
Structure
Cisatracurium
Atracurium besilate
INN
Atracurium besilate
Quality application
Ph. Eur. ASMF
Therapeutic use
Muscle relaxant
CAS number
64228-81-5
Usage
For human use
Chemical name
2,2′-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dibenzene sulfonate
Structure
Atracurium
Atipamezole hydrochloride
INN
Atipamezole hydrochloride
Quality application
Ph. Eur. ASMF, USP VMF Complete Document
Therapeutic use
Antidote to a2-adrenoceptor induced sedation (vet.)
CAS number
104075-48-1
Status
Commercially available
Usage
For veterinary use
Chemical name
4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride
Structure
Atipamezol
Thioguanine
INN
Thioguanine
Quality application
Ph. Eur. ASMF
Therapeutic use
Cytostatic
CAS number
154-42-7
Status
Commercially available
Usage
For human use
Chemical name
2-Amino-1,7-dihydro-6H-purine-6-thione
Structure
Tioguanine
Weight
1
Midazolam
INN
Midazolam
Quality application
Ph. Eur. ASMF, USP*
Therapeutic use
Sedative
CAS number
59467-70-8
Usage
For human use
Chemical name
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine monohydrochloride
Structure
Midazolam
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