AS Grindeks pazi\u0146o, ka ir pabeigusi jaunu ori\u0123in\u0101lo kandid\u0101tz\u0101\u013cu metil-GBB kl\u012bnisk\u0101 p\u0113t\u012bjuma 1. f\u0101zi. Jaun\u0101s kandid\u0101tz\u0101les paredz\u0113tas sirds un asinsvadu slim\u012bbu \u0101rst\u0113\u0161anai. Unik\u0101lo kandid\u0101tz\u0101\u013cu terapeitisk\u0101 priek\u0161roc\u012bba b\u016bs saslim\u0161anas gad\u012bjumu \u0101rst\u0113\u0161ana gan ar parenter\u0101lo z\u0101\u013cu formu, gan ar peror\u0101lo z\u0101\u013cu formu.<\/p>\n\n\n\n
Prekl\u012bniskajos p\u0113t\u012bjumos tika pier\u0101d\u012bta jaun\u0101s molekulas efektivit\u0101te, samazinot sirds infarkta izm\u0113ru un aterosklerozes progres\u0113\u0161anu un uzlabojot glikozes metabolismu. Prekl\u012bniskie un kl\u012bnisk\u0101 p\u0113t\u012bjuma 1. f\u0101zes p\u0113t\u012bjumi liecina par \u013coti labu medikamenta dro\u0161\u012bbas profilu.<\/p>\n\n\n\n
AS Grindeks valdes priek\u0161s\u0113d\u0113t\u0101js Dr. chem. Juris Hme\u013c\u0146ickis: \u201c\u0160is \u012bpa\u0161i noz\u012bm\u012bgais projekts apliecina Grindeks gatav\u012bbu tuv\u0101kaj\u0101 n\u0101kotn\u0113 pied\u0101v\u0101t pacientiem inovat\u012bvas z\u0101les miokarda infarkta un koron\u0101ras sirds slim\u012bbas \u0101rst\u0113\u0161anai. Turkl\u0101t jaunais ori\u0123in\u0101lais medikaments b\u016bs ar\u012b apliecin\u0101jums Latvijas zin\u0101tnieku z\u0101\u013cu p\u0113tniec\u012bbas kapacit\u0101tei, jo tas b\u016bs pirmais Latvij\u0101 jaunrad\u012btais un Latvijas uz\u0146\u0113muma att\u012bst\u012btais medikaments kop\u0161 pag\u0101ju\u0161\u0101 gadsimta asto\u0146desmitajiem gadiem.\u201d<\/p>\n\n\n\n
Kl\u012bnisk\u0101 p\u0113t\u012bjuma 1. f\u0101ze tika veikta sadarb\u012bb\u0101 ar pieredzes bag\u0101tiem p\u0113tniekiem, zin\u0101tniskajiem konsultantiem un p\u0113tniec\u012bbas l\u012bgumorganiz\u0101cij\u0101m atbilsto\u0161i \u201cLabai kl\u012bniskai praksei\u201d (ICH\/GCP) un Eiropas Savien\u012bbas normat\u012bvo aktu pras\u012bb\u0101m par I \u2013 IV f\u0101zes kl\u012bniskajiem p\u0113t\u012bjumiem. Savuk\u0101rt jaun\u0101s kandid\u0101tz\u0101\u013cu vielas \u0137\u012bmisko un eksperiment\u0101lo izp\u0113ti iepriek\u0161 veica Latvijas Organisk\u0101s sint\u0113zes instit\u016bta p\u0113tnieki sadarb\u012bb\u0101 ar AS Grindeks.<\/p>\n\n\n\n
Balstoties uz \u0161iem rezult\u0101tiem, \u0161obr\u012bd tiek pl\u0101noti jauno ori\u0123in\u0101lo kandid\u0101tz\u0101\u013cu 2. f\u0101zes kl\u012bniskie p\u0113t\u012bjumi. Lai \u012bstenotu v\u0113rien\u012bgo projektu, AS Grindeks ir iecer\u0113jusi piesaist\u012bt strat\u0113\u0123isku farm\u0101cijas industrijas partneri.<\/p>\n\n\n\n
Sirds un asinsvadu slim\u012bbas, joproj\u0101m ir galvenais mirst\u012bbas iemesls Latvij\u0101 un pasaul\u0113. Pasaul\u0113 2016. gad\u0101 sirds un asinsvadu slim\u012bbas bija n\u0101ves iemesls 31% gad\u012bjumu, no t\u0101m apm\u0113ram 85% \u2013 smadze\u0146u insults un miokarda infarkts, no kuriem viena tre\u0161da\u013ca n\u0101ves gad\u012bjumu cilv\u0113kos jaun\u0101kos par 70 gadiem.<\/p>\n\n\n\n
Cukura diab\u0113ts un ateroskleroze ir vieni no galvenajiem sirds un asinsvadu slim\u012bbu att\u012bst\u012bbas riska faktoriem. P\u0113c Pasaules Vesel\u012bbas organiz\u0101cijas datiem, 2019. gad\u0101 pasaul\u0113 bija 463 miljoni cilv\u0113ku, kam ir diagnostic\u0113ts cukura diab\u0113ts. Atbilsto\u0161i prognoz\u0113m, \u0161\u012bs slim\u012bbas pacientu skaits sasniegs 700 miljonus 2045. gad\u0101.<\/p>\n","protected":false},"excerpt":{"rendered":"
AS Grindeks pazi\u0146o, ka ir pabeigusi jaunu ori\u0123in\u0101lo kandid\u0101tz\u0101\u013cu metil-GBB kl\u012bnisk\u0101 p\u0113t\u012bjuma 1. f\u0101zi. Jaun\u0101s kandid\u0101tz\u0101les paredz\u0113tas sirds un asinsvadu slim\u012bbu \u0101rst\u0113\u0161anai. Unik\u0101lo kandid\u0101tz\u0101\u013cu terapeitisk\u0101…<\/p>\n","protected":false},"author":3,"featured_media":3096,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-3099","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jaunums"],"acf":[],"_links":{"self":[{"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/posts\/3099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/comments?post=3099"}],"version-history":[{"count":0,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/posts\/3099\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/media\/3096"}],"wp:attachment":[{"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/media?parent=3099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/categories?post=3099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/grindeks.com\/lv\/wp-json\/wp\/v2\/tags?post=3099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}